General Structure Information
| PDB ID | 2bxs |
| HGNC Gene Label(s) | MAOA |
| Structure Name | human monoamine oxidase a in complex with clorgyline, crystal form b |
| Resolution | 3.15Å |
| Reference | AUTH L.DE COLIBUS,M.LI,C.BINDA,A.LUSTIG,D.E.EDMONDSON,A.MATTEVITITL THREE-DIMENSIONAL STRUCTURE OF HUMAN MONOAMINE OXIDASE ATITL 2 (MAO A): RELATION TO THE STRUCTURES OF RAT MAO A AND HUMANTITL 3 MAO BREF PROC.NATL.ACAD.SCI.USA V. 102 12864 2005REFN ISSN 0027-8424PMID 16129825DOI 10.1073/PNAS.0505975102 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 490 |
| Number Of SNVs | 60 |
| Number Of Permutations | 39945 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.25 |
| p-value | 0.0 |
COSMIC
| Number Of Residues | 490 |
| Number Of SNVs | 3 |
| Number Of Permutations | 138 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.333 |
| p-value | 0.847 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
