General Structure Information
| PDB ID | 2bw0 |
| HGNC Gene Label(s) | ALDH1L1 |
| Structure Name | crystal structure of the hydrolase domain of human 10-formyltetrahydrofolate 2 dehydrogenase |
| Resolution | 1.7Å |
| Reference | AUTH P.KURSULA,H.SCHULER,S.FLODIN,P.NILSSON-EHLE,AUTH 2 D.J.OGG,P.SAVITSKY,P.NORDLUND,P.STENMARKTITL STRUCTURES OF THE HYDROLASE DOMAIN OF HUMAN 10-TITL 2 FORMYLTETRAHYDROFOLATE DEHYDROGENASE AND ITSTITL 3 COMPLEX WITH A SUBSTRATE ANALOGUE.REF ACTA CRYSTALLOGR.,SECT.D V. 62 1294 2006REFN ISSN 0907-4449PMID 17057331DOI 10.1107/S0907444906026849 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 307 |
| Number Of SNVs | 87 |
| Number Of Permutations | 16309 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.081 |
| p-value | 0.03 |
COSMIC
| Number Of Residues | 307 |
| Number Of SNVs | 4 |
| Number Of Permutations | 286 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.333 |
| p-value | 0.758 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 87 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.176 |
| p-value | 0.649 |