General Structure Information
| PDB ID | 2buj |
| HGNC Gene Label(s) | STK16 |
| Structure Name | crystal structure of the human serine-threonine kinase 16 in complex with staurosporine |
| Resolution | 2.6Å |
| Reference | AUTH J.E.DEBRECZENI,J.ESWARAN,A.BULLOCK,P.FILIPPAKOPOULOS,AUTH 2 K.KAVANAGH,A.AMOS,O.FEDOROV,F.SOBOTT,L.J.BALL,F.VON DELFT,AUTH 3 C.ARROWSMITH,M.SUNDSTROM,A.EDWARDS,S.KNAPPTITL CRYSTAL STRUCTURE OF THE HUMAN SERINE-THREONINE KINASE 16TITL 2 IN COMPLEX WITH STAUROSPORINEREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 283 |
| Number Of SNVs | 75 |
| Number Of Permutations | 31408 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.019 |
| p-value | 0.069 |
COSMIC
| Number Of Residues | 283 |
| Number Of SNVs | 3 |
| Number Of Permutations | 26 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.446 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 75 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.268 |
| p-value | 0.49 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
