General Structure Information
| PDB ID | 2bgd |
| HGNC Gene Label(s) | PTPN1 |
| Structure Name | structure-based design of protein tyrosine phosphatase-1b inhibitors |
| Resolution | 2.4Å |
| Reference | AUTH E.BLACK,J.BREED,A.L.BREEZE,K.EMBREY,R.GARCIA,T.W.GERO,AUTH 2 L.GODFREY,P.W.KENNY,A.D.MORLEY,C.A.MINSHULL,A.D.PANNIFER,AUTH 3 J.READ,A.REES,D.J.RUSSELL,D.TOADER,J.TUCKERTITL STRUCTURE-BASED DESIGN OF PROTEIN TYROSINE PHOSPHATASE-1BTITL 2 INHIBITORSREF BIOORG.MED.CHEM.LETT. V. 15 2503 2005REFN ISSN 0960-894XPMID 15863305DOI 10.1016/J.BMCL.2005.03.068 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 295 |
| Number Of SNVs | 35 |
| Number Of Permutations | 5869 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.01 |
| p-value | 0.038 |