General Structure Information
| PDB ID | 2bec |
| HGNC Gene Label(s) | CHP2 |
| Structure Name | crystal structure of chp2 in complex with its binding region in nhe1 and insights into the mechanism of ph regulation |
| Resolution | 2.7Å |
| Reference | AUTH Y.BEN AMMAR,S.TAKEDA,T.HISAMITSU,H.MORI,AUTH 2 S.WAKABAYASHITITL CRYSTAL STRUCTURE OF CHP2 COMPLEXED WITHTITL 2 NHE1-CYTOSOLIC REGION AND AN IMPLICATION FOR PHTITL 3 REGULATIONREF EMBO J. V. 25 2315 2006REFN ISSN 0261-4189PMID 16710297DOI 10.1038/SJ.EMBOJ.7601145 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 181 |
| Number Of SNVs | 59 |
| Number Of Permutations | 9051 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.161 |
| p-value | 0.0 |
COSMIC
| Number Of Residues | 181 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2627 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.2 |
| p-value | 0.336 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 59 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.098 |
| p-value | 0.681 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
