General Structure Information
| PDB ID | 2ald |
| HGNC Gene Label(s) | ALDOA |
| Structure Name | human muscle aldolase |
| Resolution | 2.1Å |
| Reference | AUTH A.DALBY,Z.DAUTER,J.A.LITTLECHILDTITL CRYSTAL STRUCTURE OF HUMAN MUSCLE ALDOLASE COMPLEXED WITHTITL 2 FRUCTOSE 1,6-BISPHOSPHATE: MECHANISTIC IMPLICATIONS.REF PROTEIN SCI. V. 8 291 1999REFN ISSN 0961-8368PMID 10048322 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 363 |
| Number Of SNVs | 91 |
| Number Of Permutations | 16036 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.06 |
| p-value | 0.113 |
COSMIC
| Number Of Residues | 363 |
| Number Of SNVs | 6 |
| Number Of Permutations | 595 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.067 |
| p-value | 0.301 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 91 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | -0.125 |
| p-value | 0.317 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
