Assessment of Structural Intolerance and Durability
General Structure Information 3lui SNX17 crystal structure of the snx17 px domain with bound sulphate 1.8Å AUTH R.GHAI,M.MOBLI,S.J.NORWOOD,A.BUGARCIC,R.D.TEASDALE,G.F.KING,AUTH 2 B.M.COLLINSTITL PHOX HOMOLOGY BAND 4.1/EZRIN/RADIXIN/MOESIN-LIKE PROTEINSTITL 2 FUNCTION AS MOLECULAR SCAFFOLDS THAT INTERACT WITH CARGOTITL 3 RECEPTORS AND RAS GTPASESREF PROC.NATL.ACAD.SCI.USA 2011REFN ESSN 1091-6490PMID 21512128DOI 10.1073/PNAS.1017110108 Variant Set Distributions Mapped Variants
General Structure Information 3lui SNX17 crystal structure of the snx17 px domain with bound sulphate 1.8Å AUTH R.GHAI,M.MOBLI,S.J.NORWOOD,A.BUGARCIC,R.D.TEASDALE,G.F.KING,AUTH 2 B.M.COLLINSTITL PHOX HOMOLOGY BAND 4.1/EZRIN/RADIXIN/MOESIN-LIKE PROTEINSTITL 2 FUNCTION AS MOLECULAR SCAFFOLDS THAT INTERACT WITH CARGOTITL 3 RECEPTORS AND RAS GTPASESREF PROC.NATL.ACAD.SCI.USA 2011REFN ESSN 1091-6490PMID 21512128DOI 10.1073/PNAS.1017110108 Variant Set Distributions Mapped Variants
General Structure Information 3lui SNX17 crystal structure of the snx17 px domain with bound sulphate 1.8Å AUTH R.GHAI,M.MOBLI,S.J.NORWOOD,A.BUGARCIC,R.D.TEASDALE,G.F.KING,AUTH 2 B.M.COLLINSTITL PHOX HOMOLOGY BAND 4.1/EZRIN/RADIXIN/MOESIN-LIKE PROTEINSTITL 2 FUNCTION AS MOLECULAR SCAFFOLDS THAT INTERACT WITH CARGOTITL 3 RECEPTORS AND RAS GTPASESREF PROC.NATL.ACAD.SCI.USA 2011REFN ESSN 1091-6490PMID 21512128DOI 10.1073/PNAS.1017110108 Variant Set Distributions Mapped Variants
General Structure Information 4fzs SNX1 structure of human snx1 bar domain 2.8Å AUTH J.R.T.VAN WEERING,R.B.SESSIONS,C.J.TRAER,D.P.KLOER,AUTH 2 V.K.BHATIA,D.STAMOU,J.H.HURLEY,P.J.CULLENTITL MOLECULAR INSIGHT INTO VESICLE-TO-TUBULE MEMBRANE REMODELINGTITL 2 BY SNX-BAR PROTEINSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2d7n FLNC solution structure of the 16th filamin domain from human filamin c -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 16TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN CREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2emv ZNF268 solution structure of the c2h2 type zinc finger (region 859- 889) of human zinc finger protein 268 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 859-889) OF HUMAN ZINC FINGER PROTEIN 268REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3v8o FLNC human filamin c ig – like domains 4 and 5 2.8Å AUTH R.SETHI,J.SEPPALA,H.TOSSAVAINEN,M.YLILAURI,S.RUSKAMO,AUTH 2 O.T.PENTIKAINEN,U.PENTIKAINEN,P.PERMI,J.YLANNETITL A NOVEL STRUCTURAL UNIT IN THE N-TERMINAL REGION OFTITL 2 FILAMINS.REF J.BIOL.CHEM. V. 289 8588 2014REFN ISSN 0021-9258PMID 24469451DOI 10.1074/JBC.M113.537456 Variant Set Distributions Mapped Variants
General Structure Information 3v8o FLNC human filamin c ig – like domains 4 and 5 2.8Å AUTH R.SETHI,J.SEPPALA,H.TOSSAVAINEN,M.YLILAURI,S.RUSKAMO,AUTH 2 O.T.PENTIKAINEN,U.PENTIKAINEN,P.PERMI,J.YLANNETITL A NOVEL STRUCTURAL UNIT IN THE N-TERMINAL REGION OFTITL 2 FILAMINS.REF J.BIOL.CHEM. V. 289 8588 2014REFN ISSN 0021-9258PMID 24469451DOI 10.1074/JBC.M113.537456 Variant Set Distributions Mapped Variants
General Structure Information 3v8o FLNC human filamin c ig – like domains 4 and 5 2.8Å AUTH R.SETHI,J.SEPPALA,H.TOSSAVAINEN,M.YLILAURI,S.RUSKAMO,AUTH 2 O.T.PENTIKAINEN,U.PENTIKAINEN,P.PERMI,J.YLANNETITL A NOVEL STRUCTURAL UNIT IN THE N-TERMINAL REGION OFTITL 2 FILAMINS.REF J.BIOL.CHEM. V. 289 8588 2014REFN ISSN 0021-9258PMID 24469451DOI 10.1074/JBC.M113.537456 Variant Set Distributions Mapped Variants
General Structure Information 1v5w DMC1 crystal structure of the human dmc1 protein 3.2Å AUTH T.KINEBUCHI,W.KAGAWA,R.ENOMOTO,K.TANAKA,K.MIYAGAWA,AUTH 2 T.SHIBATA,H.KURUMIZAKA,S.YOKOYAMATITL STRUCTURAL BASIS FOR OCTAMERIC RING FORMATION AND DNATITL 2 INTERACTION OF THE HUMAN HOMOLOGOUS-PAIRING PROTEIN DMC1REF MOL.CELL V. 14 363 2004REFN ISSN 1097-2765PMID 15125839DOI 10.1016/S1097-2765(04)00218-7 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]