General Structure Information
| PDB ID | 1z6c |
| HGNC Gene Label(s) | PROS1 |
| Structure Name | solution structure of an egf pair (egf34) from vitamin k- dependent protein s |
| Resolution | -1.0Å |
| Reference | AUTH T.DRAKENBERG,H.GHASRIANI,E.THULIN,A.MURANYI,AUTH 2 A.ANNILA,J.STENFLOTITL SOLUTION STRUCTURE OF THE CA(2+)-BINDING EGF3-4TITL 2 PAIR FROM VITAMIN K-DEPENDENT PROTEIN S:TITL 3 IDENTIFICATION OF AN UNUSUAL FOLD IN EGF3.REF BIOCHEMISTRY V. 44 8782 2005REFN ISSN 0006-2960PMID 15952784DOI 10.1021/BI050101F |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 87 |
| Number Of SNVs | 19 |
| Number Of Permutations | 2576 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.099 |
| p-value | 0.544 |
COSMIC
| Number Of Residues | 87 |
| Number Of SNVs | 3 |
| Number Of Permutations | 18 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 19 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.368 |
| p-value | 0.362 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
