General Structure Information
| PDB ID | 1yc0 |
| HGNC Gene Label(s) | HGFAC |
| Structure Name | short form hgfa with first kunitz domain from hai-1 |
| Resolution | 2.6Å |
| Reference | AUTH S.SHIA,J.STAMOS,D.KIRCHHOFER,B.FAN,J.WU,R.T.CORPUZ,AUTH 2 L.SANTELL,R.A.LAZARUS,C.EIGENBROTTITL CONFORMATIONAL LABILITY IN SERINE PROTEASE ACTIVE SITES:TITL 2 STRUCTURES OF HEPATOCYTE GROWTH FACTOR ACTIVATOR (HGFA)TITL 3 ALONE AND WITH THE INHIBITORY DOMAIN FROM HGFA INHIBITOR-1B.REF J.MOL.BIOL. V. 346 1335 2005REFN ISSN 0022-2836PMID 15713485DOI 10.1016/J.JMB.2004.12.048 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 247 |
| Number Of SNVs | 86 |
| Number Of Permutations | 8760 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.174 |
| p-value | 0.281 |
COSMIC
| Number Of Residues | 247 |
| Number Of SNVs | 5 |
| Number Of Permutations | 580 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.1 |
| p-value | 0.733 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 86 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.205 |
| p-value | 0.505 |