General Structure Information
| PDB ID | 1wsv |
| HGNC Gene Label(s) | AMT |
| Structure Name | crystal structure of human t-protein of glycine cleavage system |
| Resolution | 2.6Å |
| Reference | AUTH K.OKAMURA-IKEDA,H.HOSAKA,M.YOSHIMURA,E.YAMASHITA,AUTH 2 S.TOMA,A.NAKAGAWA,K.FUJIWARA,Y.MOTOKAWA,H.TANIGUCHITITL CRYSTAL STRUCTURE OF HUMAN T-PROTEIN OF GLYCINETITL 2 CLEAVAGE SYSTEM AT 2.0A RESOLUTION AND ITSTITL 3 IMPLICATION FOR UNDERSTANDING NON-KETOTICTITL 4 HYPERGLYCINEMIAREF J.MOL.BIOL. V. 351 1146 2005REFN ISSN 0022-2836PMID 16051266DOI 10.1016/J.JMB.2005.06.056 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 371 |
| Number Of SNVs | 101 |
| Number Of Permutations | 14753 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.222 |
| p-value | 0.043 |
ClinVar
| Number Of Residues | 371 |
| Number Of SNVs | 10 |
| Number Of Permutations | 1459 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.267 |
| p-value | 0.025 |
COSMIC
| Number Of Residues | 371 |
| Number Of SNVs | 3 |
| Number Of Permutations | 64 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.333 |
| p-value | 0.178 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 101 |
| Number Of ClinVar SNVs | 10 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.171 |
| p-value | 0.018 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 101 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.304 |
| p-value | 0.21 |