General Structure Information
| PDB ID | 1w6u |
| HGNC Gene Label(s) | DECR1 |
| Structure Name | structure of human decr ternary complex |
| Resolution | 1.75Å |
| Reference | AUTH M.S.ALPHEY,W.YU,E.BYRES,D.LI,W.N.HUNTERTITL STRUCTURE AND REACTIVITY OF HUMAN MITOCHONDRIALTITL 2 2,4-DIENOYL-COA REDUCTASE: ENZYME-LIGANDTITL 3 INTERACTIONS IN A DISTINCTIVE SHORT-CHAINTITL 4 REDUCTASE ACTIVE SITEREF J.BIOL.CHEM. V. 280 3068 2005REFN ISSN 0021-9258PMID 15531764DOI 10.1074/JBC.M411069200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 285 |
| Number Of SNVs | 80 |
| Number Of Permutations | 26344 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.024 |
| p-value | 0.75 |
COSMIC
| Number Of Residues | 285 |
| Number Of SNVs | 3 |
| Number Of Permutations | 170 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.667 |
| p-value | 0.536 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 80 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.44 |
| p-value | 0.511 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
