1V89.A | ARHGAP25

PDB ID	1v89
HGNC Gene Label(s)	ARHGAP25
Structure Name	solution structure of the pleckstrin homology domain of human kiaa0053 protein
Resolution	-1.0Å
Reference	AUTH H.LI,N.TOCHIO,S.KOSHIBA,M.INOUE,H.HIROTA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PLECKSTRIN HOMOLOGYTITL 2 DOMAIN OF HUMAN KIAA0053 PROTEINREF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:69002437	rs143944095	K>R	A:10	(-7.61, 2.04, 7.73)
2:69002447		W>C	A:13	(3.04, -3.42, 10.23)
2:69002494		F>S	A:29	(1.18, 0.96, 4.33)
2:69002506	rs201284610 COSM1022368 COSM1592340 COSM3972310 COSM3055753	A>V	A:33	(-5.04, 13.61, 4.82)
2:69002518		Y>C	A:37	(1.47, 9.35, 4.13)
2:69002520		Y>H	A:38	(6.04, 3.40, 3.24)
2:69002523		Y>H	A:39	(5.56, 5.62, 8.36)
2:69002540		D>E	A:44	(10.53, 6.45, 12.41)
2:69002542	COSM1409082 COSM1409081	T>M	A:45	(8.90, 10.43, 13.35)
2:69009390	rs374715070	T>I	A:57	(-5.71, 3.71, -10.49)
2:69009395		K>E	A:59	(-5.68, -1.53, -11.52)
2:69009408		T>K	A:63	(-2.54, -14.56, -6.94)
2:69009410	COSM4095228 COSM4095227 COSM4095229 COSM4095230	N>Y	A:64	(-2.41, -18.60, -9.27)
2:69009413	rs368863689	P>A	A:65	(-4.61, -18.55, -12.79)
2:69009443		I>V	A:75	(-2.14, 2.15, -5.03)
2:69014989	rs201820537	R>C	A:84	(9.95, 3.77, -21.98)
2:69014998		Q>E	A:87	(6.67, 5.34, -11.95)
2:69015001		D>N	A:88	(6.61, 0.54, -10.84)
2:69015005		S>Y	A:89	(2.28, 0.28, -9.51)
2:69015008	rs555558513	Y>C	A:90	(2.96, 1.83, -3.92)
2:69015032	rs146399222	A>V	A:98	(-12.03, -7.03, 6.27)
2:69015037		M>V	A:100	(-8.56, -5.67, 0.70)
2:69015049		V>I	A:104	(-9.34, -0.67, -1.36)
2:69015050		V>A	A:104	(-9.34, -0.67, -1.36)

1V89.A | ARHGAP25.