General Structure Information
| PDB ID | 1urf |
| HGNC Gene Label(s) | PKN1 |
| Structure Name | hr1b domain from prk1 |
| Resolution | -1.0Å |
| Reference | AUTH D.OWEN,P.N.LOWE,D.NIETLISPACH,C.E.BROSNAN,AUTH 2 D.Y.CHIRGADZE,P.J.PARKER,T.L.BLUNDELL,H.R.MOTTTITL MOLECULAR DISSECTION OF THE INTERACTION BETWEENTITL 2 THE SMALL G PROTEINS RAC1 AND RHOA AND PROTEINTITL 3 KINASE C-RELATED KINASE 1 (PRK1)REF J.BIOL.CHEM. V. 278 50578 2003REFN ISSN 0021-9258PMID 14514689DOI 10.1074/JBC.M304313200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 78 |
| Number Of SNVs | 21 |
| Number Of Permutations | 12030 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.186 |
| p-value | 0.898 |
COSMIC
| Number Of Residues | 78 |
| Number Of SNVs | 4 |
| Number Of Permutations | 194 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.167 |
| p-value | 0.801 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 21 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.252 |
| p-value | 0.983 |