1UNL.B | CDK5

General Structure Information

PDB ID 1unl
HGNC Gene Label(s) CDK5
Structure Name structural mechanism for the inhibition of cd5-p25 from the roscovitine, aloisine and indirubin.
Resolution 2.2Å
Reference AUTH M.MAPELLI,L.MASSIMILINAO,C.CROVACE,M.A.SEELIGER,L.-H.TSAI,AUTH 2 L.MEIJER,A.MUSACCHIOTITL MECHANISM OF CDK5/P25 BINDING BY CDK INHIBITORSREF J.MED.CHEM. V. 48 671 2005REFN ISSN 0022-2623PMID 15689152DOI 10.1021/JM049323M

Variant Set Distributions

ExAC Variants

Number Of Residues 292
Number Of SNVs 39
Number Of Permutations 21309
Optimal Distance Threshold 5.0
K Statistic 0.011
p-value 0.543

Mapped Variants

[+] ExAC Missense Variants