General Structure Information
| PDB ID | 1unh |
| HGNC Gene Label(s) | CDK5R1 |
| Structure Name | structural mechanism for the inhibition of cdk5-p25 by roscovitine, aloisine and indirubin. |
| Resolution | 2.35Å |
| Reference | AUTH M.MAPELLI,L.MASSIMILINAO,C.CROVACE,M.A.SEELIGER,L.-H.TSAI,AUTH 2 L.MEIJER,A.MUSACCHIOTITL MECHANISM OF CDK5/P25 BINDING BY CDK INHIBITORSREF J.MED.CHEM. V. 48 671 2005REFN ISSN 0022-2623PMID 15689152DOI 10.1021/JM049323M |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 148 |
| Number Of SNVs | 22 |
| Number Of Permutations | 5597 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.143 |
| p-value | 0.738 |