General Structure Information
| PDB ID | 1t5c |
| HGNC Gene Label(s) | CENPE |
| Structure Name | crystal structure of the motor domain of human kinetochore protein cenp-e |
| Resolution | 2.5Å |
| Reference | AUTH I.GARCIA-SAEZ,T.YEN,R.H.WADE,F.KOZIELSKITITL CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF THE HUMANTITL 2 KINETOCHORE PROTEIN CENP-E.REF J.MOL.BIOL. V. 340 1107 2004REFN ISSN 0022-2836PMID 15236970DOI 10.1016/J.JMB.2004.05.053 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 310 |
| Number Of SNVs | 39 |
| Number Of Permutations | 6910 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.049 |
| p-value | 0.664 |
COSMIC
| Number Of Residues | 310 |
| Number Of SNVs | 3 |
| Number Of Permutations | 45 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.333 |
| p-value | 0.74 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
