General Structure Information
| PDB ID | 1svc |
| HGNC Gene Label(s) | NFKB1 |
| Structure Name | nfkb p50 homodimer bound to dna |
| Resolution | 2.6Å |
| Reference | AUTH C.W.MULLER,F.A.REY,M.SODEOKA,G.L.VERDINE,AUTH 2 S.C.HARRISONTITL STRUCTURE OF THE NF-KAPPA B P50 HOMODIMER BOUND TOTITL 2 DNA.REF NATURE V. 373 311 1995REFN ISSN 0028-0836PMID 7830764DOI 10.1038/373311A0 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 311 |
| Number Of SNVs | 29 |
| Number Of Permutations | 24791 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.591 |
| p-value | 0.015 |
COSMIC
| Number Of Residues | 311 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1127 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.167 |
| p-value | 0.705 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 29 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 40.0 |
| K Statistic | -0.487 |
| p-value | 0.392 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
