General Structure Information
| PDB ID | 1sos |
| HGNC Gene Label(s) | SOD1 |
| Structure Name | atomic structures of wild-type and thermostable mutant recombinant human cu, zn superoxide dismutase |
| Resolution | 2.5Å |
| Reference | AUTH H.E.PARGE,R.A.HALLEWELL,J.A.TAINERTITL ATOMIC STRUCTURES OF WILD-TYPE AND THERMOSTABLETITL 2 MUTANT RECOMBINANT HUMAN CU,ZN SUPEROXIDETITL 3 DISMUTASE.REF PROC.NATL.ACAD.SCI.USA V. 89 6109 1992REFN ISSN 0027-8424PMID 1463506DOI 10.1073/PNAS.89.13.6109 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 153 |
| Number Of SNVs | 19 |
| Number Of Permutations | 1422 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.029 |
| p-value | 0.093 |
ClinVar
| Number Of Residues | 153 |
| Number Of SNVs | 26 |
| Number Of Permutations | 2057 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.28 |
| p-value | 0.05 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 19 |
| Number Of ClinVar SNVs | 26 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.116 |
| p-value | 0.003 |