1SHY.A | HGF

General Structure Information

PDB ID 1shy
HGNC Gene Label(s) HGF
Structure Name the crystal structure of hgf beta-chain in complex with the sema domain of the met receptor.
Resolution 3.22Å
Reference AUTH J.STAMOS,R.A.LAZARUS,X.YAO,D.KIRCHHOFER,C.WIESMANNTITL CRYSTAL STRUCTURE OF THE HGF BETA-CHAIN IN COMPLEX WITH THETITL 2 SEMA DOMAIN OF THE MET RECEPTOR.REF EMBO J. V. 23 2325 2004REFN ISSN 0261-4189PMID 15167892DOI 10.1038/SJ.EMBOJ.7600243

Variant Set Distributions

ExAC Variants

Number Of Residues 228
Number Of SNVs 46
Number Of Permutations 5206
Optimal Distance Threshold 16.0
K Statistic 0.297
p-value 0.521
COSMIC

Number Of Residues 228
Number Of SNVs 3
Number Of Permutations 1
Optimal Distance Threshold 12.0
K Statistic 0.333
p-value 1.0

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants