General Structure Information
| PDB ID | 1rx0 |
| HGNC Gene Label(s) | ACAD8 |
| Structure Name | crystal structure of isobutyryl-coa dehydrogenase complexed with substrate/ligand. |
| Resolution | 1.77Å |
| Reference | AUTH K.P.BATTAILE,T.V.NGUYEN,J.VOCKLEY,J.J.KIMTITL STRUCTURES OF ISOBUTYRYL-COA DEHYDROGENASE ANDTITL 2 ENZYME-PRODUCT COMPLEX: COMPARISON WITHTITL 3 ISOVALERYL- AND SHORT-CHAIN ACYL-COATITL 4 DEHYDROGENASES.REF J.BIOL.CHEM. V. 279 16526 2004REFN ISSN 0021-9258PMID 14752098DOI 10.1074/JBC.M400034200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 383 |
| Number Of SNVs | 104 |
| Number Of Permutations | 65543 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.04 |
| p-value | 0.935 |
ClinVar
| Number Of Residues | 383 |
| Number Of SNVs | 6 |
| Number Of Permutations | 3395 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.2 |
| p-value | 0.763 |
COSMIC
| Number Of Residues | 383 |
| Number Of SNVs | 4 |
| Number Of Permutations | 178 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.167 |
| p-value | 0.678 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 104 |
| Number Of ClinVar SNVs | 6 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.075 |
| p-value | 0.783 |
Cosmic vs. ExAC
