General Structure Information
| PDB ID | 1rv6 |
| HGNC Gene Label(s) | PGF |
| Structure Name | crystal structure of plgf in complex with domain 2 of vegfr1 |
| Resolution | 2.45Å |
| Reference | AUTH H.W.CHRISTINGER,G.FUH,A.M.DE VOS,C.WIESMANNTITL THE CRYSTAL STRUCTURE OF PLACENTAL GROWTH FACTOR IN COMPLEXTITL 2 WITH DOMAIN 2 OF VASCULAR ENDOTHELIAL GROWTH FACTORTITL 3 RECEPTOR-1.REF J.BIOL.CHEM. V. 279 10382 2004REFN ISSN 0021-9258PMID 14684734DOI 10.1074/JBC.M313237200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 95 |
| Number Of SNVs | 33 |
| Number Of Permutations | 17599 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.453 |
| p-value | 0.17 |
COSMIC
| Number Of Residues | 95 |
| Number Of SNVs | 4 |
| Number Of Permutations | 117 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.131 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 33 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.269 |
| p-value | 0.582 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
