General Structure Information
| PDB ID | 1rjb |
| HGNC Gene Label(s) | FLT3 |
| Structure Name | crystal structure of flt3 |
| Resolution | 2.1Å |
| Reference | AUTH J.GRIFFITH,J.BLACK,C.FAERMAN,L.SWENSON,M.WYNN,F.LU,AUTH 2 J.LIPPKE,K.SAXENATITL THE STRUCTURAL BASIS FOR AUTOINHIBITION OF FLT3 BYTITL 2 THE JUXTAMEMBRANE DOMAIN.REF MOL.CELL V. 13 169 2004REFN ISSN 1097-2765PMID 14759363DOI 10.1016/S1097-2765(03)00505-7 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 258 |
| Number Of SNVs | 63 |
| Number Of Permutations | 31684 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.053 |
| p-value | 0.958 |
COSMIC
| Number Of Residues | 258 |
| Number Of SNVs | 17 |
| Number Of Permutations | 10806 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.184 |
| p-value | 0.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 63 |
| Number Of COSMIC SNVs | 12 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.375 |
| p-value | 0.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
