General Structure Information
| PDB ID | 1rgo |
| HGNC Gene Label(s) | ZFP36L2 |
| Structure Name | structural basis for recognition of the mrna class ii au- rich element by the tandem zinc finger domain of tis11d |
| Resolution | -1.0Å |
| Reference | AUTH B.P.HUDSON,M.A.MARTINEZ-YAMOUT,H.J.DYSON,P.E.WRIGHTTITL RECOGNITION OF THE MRNA AU-RICH ELEMENT BY THETITL 2 ZINC FINGER DOMAIN OF TIS11D.REF NAT.STRUCT.MOL.BIOL. V. 11 257 2004REFN ISSN 1545-9993PMID 14981510DOI 10.1038/NSMB738 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 70 |
| Number Of SNVs | 9 |
| Number Of Permutations | 2567 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.194 |
| p-value | 0.483 |
COSMIC
| Number Of Residues | 70 |
| Number Of SNVs | 5 |
| Number Of Permutations | 686 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.3 |
| p-value | 0.051 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 9 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.189 |
| p-value | 0.081 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
