General Structure Information
| PDB ID | 1qty |
| HGNC Gene Label(s) | FLT1 |
| Structure Name | vascular endothelial growth factor in complex with domain 2 of the flt-1 receptor |
| Resolution | 2.7Å |
| Reference | AUTH M.A.STAROVASNIK,H.W.CHRISTINGER,C.WIESMANN,AUTH 2 M.A.CHAMPE,A.M.DE VOS,N.J.SKELTONTITL SOLUTION STRUCTURE OF THE VEGF-BINDING DOMAIN OFTITL 2 FLT-1: COMPARISON OF ITS FREE AND BOUND STATES.REF J.MOL.BIOL. V. 293 531 1999REFN ISSN 0022-2836PMID 10543948DOI 10.1006/JMBI.1999.3134 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 94 |
| Number Of SNVs | 23 |
| Number Of Permutations | 1629 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.047 |
| p-value | 0.906 |
COSMIC
| Number Of Residues | 94 |
| Number Of SNVs | 4 |
| Number Of Permutations | 369 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.167 |
| p-value | 0.287 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 23 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | -0.202 |
| p-value | 0.677 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
