General Structure Information
| PDB ID | 1ovl |
| HGNC Gene Label(s) | NR4A2 |
| Structure Name | crystal structure of nurr1 lbd |
| Resolution | 2.2Å |
| Reference | AUTH Z.WANG,G.BENOIT,J.LIU,S.PRASAD,P.AARNISALO,X.LIU,AUTH 2 H.XU,N.WALKER,T.PERLMANNTITL STRUCTURE AND FUNCTION OF NURR1 IDENTIFIES A CLASSTITL 2 OF LIGAND-INDEPENDENT NUCLEAR RECEPTORSREF NATURE V. 423 555 2003REFN ISSN 0028-0836PMID 12774125DOI 10.1038/NATURE01645 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 226 |
| Number Of SNVs | 45 |
| Number Of Permutations | 6893 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.058 |
| p-value | 0.806 |
COSMIC
| Number Of Residues | 226 |
| Number Of SNVs | 5 |
| Number Of Permutations | 66 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.2 |
| p-value | 0.634 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 45 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.566 |
| p-value | 0.087 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
