General Structure Information
| PDB ID | 1oip |
| HGNC Gene Label(s) | TTPA |
| Structure Name | the molecular basis of vitamin e retention: structure of human alpha-tocopherol transfer protein |
| Resolution | 1.95Å |
| Reference | AUTH R.MEIER,T.TOMIZAKI,C.SCHULZE-BRIESE,U.BAUMANN,AUTH 2 A.STOCKERTITL THE MOLECULAR BASIS OF VITAMIN E RETENTION:TITL 2 STRUCTURE OF HUMAN ALPHA-TOCOPHEROL TRANSFERTITL 3 PROTEINREF J.MOL.BIOL. V. 331 725 2003REFN ISSN 0022-2836PMID 12899840DOI 10.1016/S0022-2836(03)00724-1 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 251 |
| Number Of SNVs | 63 |
| Number Of Permutations | 21476 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.039 |
| p-value | 0.196 |
ClinVar
| Number Of Residues | 251 |
| Number Of SNVs | 9 |
| Number Of Permutations | 3238 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.278 |
| p-value | 0.493 |
COSMIC
| Number Of Residues | 251 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1048 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.2 |
| p-value | 0.688 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 63 |
| Number Of ClinVar SNVs | 9 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | -0.023 |
| p-value | 0.973 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 63 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.095 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
COSMIC PathProx Analysis
