General Structure Information
| PDB ID | 1nr1 |
| HGNC Gene Label(s) | GLUD1 |
| Structure Name | crystal structure of the r463a mutant of human glutamate dehydrogenase |
| Resolution | 3.3Å |
| Reference | AUTH S.BANERJEE,T.SCHMIDT,J.FANG,C.A.STANLEY,T.J.SMITHTITL STRUCTURAL STUDIES ON ADP ACTIVATION OF MAMMALIANTITL 2 GLUTAMATE DEHYDROGENASE AND THE EVOLUTION OFTITL 3 REGULATIONREF BIOCHEMISTRY V. 42 3446 2003REFN ISSN 0006-2960PMID 12653548DOI 10.1021/BI0206917 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 496 |
| Number Of SNVs | 58 |
| Number Of Permutations | 20565 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.013 |
| p-value | 0.559 |
ClinVar
| Number Of Residues | 496 |
| Number Of SNVs | 9 |
| Number Of Permutations | 2664 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.167 |
| p-value | 0.0 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 58 |
| Number Of ClinVar SNVs | 9 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.649 |
| p-value | 0.0 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
