1NLW.A | MXD1 – ASTRID

1NLW.A | MXD1

PDB ID	1nlw
HGNC Gene Label(s)	MXD1
Structure Name	crystal structure of mad-max recognizing dna
Resolution	2.0Å
Reference	AUTH S.K.NAIR,S.K.BURLEYTITL X-RAY STRUCTURES OF MYC-MAX AND MAD-MAXTITL 2 RECOGNIZING DNA: MOLECULAR BASES OF REGULATION BYTITL 3 PROTO-ONCOGENIC TRANSCRIPTION FACTORSREF CELL(CAMBRIDGE,MASS.) V. 112 193 2003REFN ISSN 0092-8674PMID 12553908DOI 10.1016/S0092-8674(02)01284-9

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:70143349		S>N	A:2	(-25.50, 3.83, -16.04)
2:70162493		L>I	A:17	(-5.87, 4.98, -3.46)
2:70162503	rs200426575	C>Y	A:20	(-2.96, 8.19, -0.24)
2:70162520		G>R	A:26	(6.99, 11.54, 0.66)
2:70162533		L>P	A:30	(12.91, 5.72, -0.96)
2:70162541	rs570538720 COSM1641965	E>K	A:33	(16.70, 10.67, -7.30)
2:70162550	COSM170443	R>G	A:36	(12.04, 3.19, -9.91)
2:70162551		R>Q	A:36	(12.04, 3.19, -9.91)
2:70162553		H>Y	A:37	(4.73, 4.22, -8.06)
2:70162556		T>A	A:38	(6.08, -0.06, -8.44)
2:70162560	COSM1409161	T>M	A:39	(2.83, 0.38, -5.89)
2:70162575		T>I	A:44	(8.43, -2.61, 0.32)
2:70164369		K>N	A:52	(14.99, 1.42, 11.48)
2:70164390	rs539482630	K>N	A:59	(17.81, 0.39, 19.98)
2:70164394	rs377129045	V>I	A:61	(13.52, 3.24, 25.63)
2:70164397		H>Y	A:62	(17.89, -0.11, 26.77)
2:70164407		D>G	A:65	(16.97, 2.53, 31.54)
2:70164416		Q>R	A:68	(17.47, 7.03, 33.77)
2:70164419		R>Q	A:69	(19.32, 1.82, 35.59)
2:70164428	COSM1022469	R>Q	A:72	(19.45, 6.34, 39.45)
2:70164439		R>W	A:76	(23.79, 6.33, 44.52)
2:70164452		K>R	A:80	(30.69, 10.17, 48.99)