General Structure Information
| PDB ID | 1nkr |
| HGNC Gene Label(s) | KIR2DL1 |
| Structure Name | inhibitory receptor (p58-cl42) for human natural killer cells |
| Resolution | 1.7Å |
| Reference | AUTH Q.R.FAN,L.MOSYAK,C.C.WINTER,N.WAGTMANN,E.O.LONG,AUTH 2 D.C.WILEYTITL STRUCTURE OF THE INHIBITORY RECEPTOR FOR HUMANTITL 2 NATURAL KILLER CELLS RESEMBLES HAEMATOPOIETICTITL 3 RECEPTORS.REF NATURE V. 389 96 1997REFN ISSN 0028-0836PMID 9288975DOI 10.1038/38028 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 195 |
| Number Of SNVs | 36 |
| Number Of Permutations | 6089 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.038 |
| p-value | 0.168 |
COSMIC
| Number Of Residues | 195 |
| Number Of SNVs | 11 |
| Number Of Permutations | 9776 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.109 |
| p-value | 0.551 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 36 |
| Number Of COSMIC SNVs | 12 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | -0.024 |
| p-value | 0.707 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
