General Structure Information
| PDB ID | 1ncu |
| HGNC Gene Label(s) | TTN |
| Structure Name | titin module m5, n-terminally extended, nmr |
| Resolution | -1.0Å |
| Reference | AUTH M.PFUHL,S.IMPROTA,A.S.POLITOUS,A.PASTORETITL WHEN A MODULE IS ALSO A DOMAIN: THE ROLE OF THE NTITL 2 TERMINUS IN THE STABILITY AND THE DYNAMICS OFTITL 3 IMMUNOGLOBULIN DOMAINS FROM TITIN.REF J.MOL.BIOL. V. 265 242 1997REFN ISSN 0022-2836PMID 9020985DOI 10.1006/JMBI.1996.0725 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 91 |
| Number Of SNVs | 35 |
| Number Of Permutations | 8254 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.156 |
COSMIC
| Number Of Residues | 91 |
| Number Of SNVs | 4 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 35 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.269 |
| p-value | 0.464 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
