General Structure Information
| PDB ID | 1n3l |
| HGNC Gene Label(s) | YARS |
| Structure Name | crystal structure of a human aminoacyl-trna synthetase cytokine |
| Resolution | 1.18Å |
| Reference | AUTH X.-L.YANG,R.J.SKENE,D.E.MCREE,P.SCHIMMELTITL CRYSTAL STRUCTURE OF A HUMAN AMINOACYL-TRNA SYNTHETASETITL 2 CYTOKINEREF PROC.NATL.ACAD.SCI.USA V. 99 15369 2002REFN ISSN 0027-8424PMID 12427973DOI 10.1073/PNAS.242611799 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 332 |
| Number Of SNVs | 65 |
| Number Of Permutations | 39782 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.015 |
| p-value | 0.742 |
ClinVar
| Number Of Residues | 332 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1035 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.5 |
| p-value | 0.829 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 65 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.147 |
| p-value | 0.817 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
