General Structure Information
| PDB ID | 1mq0 |
| HGNC Gene Label(s) | CDA |
| Structure Name | crystal structure of human cytidine deaminase |
| Resolution | 2.4Å |
| Reference | AUTH S.J.CHUNG,J.C.FROMME,G.L.VERDINETITL STRUCTURE OF HUMAN CYTIDINE DEAMINASE BOUND TO A POTENTTITL 2 INHIBITORREF J.MED.CHEM. V. 48 658 2005REFN ISSN 0022-2623PMID 15689149DOI 10.1021/JM0496279 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 130 |
| Number Of SNVs | 38 |
| Number Of Permutations | 3380 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.236 |
| p-value | 0.827 |
COSMIC
| Number Of Residues | 130 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1151 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.3 |
| p-value | 0.817 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 38 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | -0.081 |
| p-value | 0.931 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
