General Structure Information
| PDB ID | 1mmp |
| HGNC Gene Label(s) | MMP7 |
| Structure Name | matrilysin complexed with carboxylate inhibitor |
| Resolution | 2.3Å |
| Reference | AUTH M.F.BROWNER,W.W.SMITH,A.L.CASTELHANOTITL MATRILYSIN-INHIBITOR COMPLEXES: COMMON THEMESTITL 2 AMONG METALLOPROTEASES.REF BIOCHEMISTRY V. 34 6602 1995REFN ISSN 0006-2960PMID 7756291DOI 10.1021/BI00020A004 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 165 |
| Number Of SNVs | 65 |
| Number Of Permutations | 3109 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.191 |
| p-value | 0.228 |
COSMIC
| Number Of Residues | 165 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.333 |
| p-value | 0.189 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
