General Structure Information
| PDB ID | 1mkj |
| HGNC Gene Label(s) | KIF5B |
| Structure Name | human kinesin motor domain with docked neck linker |
| Resolution | 2.7Å |
| Reference | AUTH C.V.SINDELAR,M.J.BUDNY,S.RICE,N.NABER,R.FLETTERICK,AUTH 2 R.COOKETITL TWO CONFORMATIONS IN THE HUMAN KINESIN POWERTITL 2 STROKE DEFINED BY X-RAY CRYSTALLOGRAPHY AND EPRTITL 3 SPECTROSCOPY.REF NAT.STRUCT.BIOL. V. 9 844 2002REFN ISSN 1072-8368PMID 12368902 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 336 |
| Number Of SNVs | 36 |
| Number Of Permutations | 10213 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.017 |
| p-value | 0.852 |
COSMIC
| Number Of Residues | 336 |
| Number Of SNVs | 4 |
| Number Of Permutations | 762 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 36 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.156 |
| p-value | 0.743 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
