1L9L.A | GNLY – ASTRID

1L9L.A | GNLY

PDB ID	1l9l
HGNC Gene Label(s)	GNLY
Structure Name	granulysin from human cytolytic t lymphocytes
Resolution	0.92Å
Reference	AUTH D.H.ANDERSON,M.R.SAWAYA,D.CASCIO,W.ERNST,R.MODLIN,AUTH 2 A.KRENSKY,D.EISENBERGTITL GRANULYSIN CRYSTAL STRUCTURE AND ATITL 2 STRUCTURE-DERIVED LYTIC MECHANISMREF J.MOL.BIOL. V. 325 355 2002REFN ISSN 0022-2836PMID 12488100DOI 10.1016/S0022-2836(02)01234-2

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:85923114	rs35146240	R>C	A:2	(0.57, 21.08, 15.41)
2:85923115	COSM1023399	R>H	A:2	(0.57, 21.08, 15.41)
2:85923130		C>Y	A:7	(0.11, 11.02, 16.19)
2:85923133	rs138334587	L>P	A:8	(-4.13, 9.67, 14.46)
2:85923139		I>T	A:10	(3.63, 9.64, 12.32)
2:85923165		D>N	A:19	(5.93, -6.59, 7.52)
2:85923166	rs572625963	D>G	A:19	(5.93, -6.59, 7.52)
2:85923168		K>E	A:20	(5.95, -9.23, 13.11)
2:85923169	rs61731721	K>T	A:20	(5.95, -9.23, 13.11)
2:85923175	rs141685032	T>S	A:22	(9.31, -5.93, 15.55)
2:85924631		R>S	A:24	(15.69, -4.89, 13.37)
2:85924642		N>S	A:28	(14.74, 0.45, 11.21)
2:85924648		A>V	A:30	(10.74, 5.61, 12.75)
2:85924653	COSM1208428	R>W	A:32	(12.76, 4.39, 6.60)
2:85924663		R>K	A:35	(14.63, 12.15, 5.99)
2:85924666		T>M	A:36	(8.11, 10.99, 2.53)
2:85924672		R>K	A:38	(5.42, 19.96, -0.94)
2:85924678	COSM1023401	R>Q	A:40	(3.15, 22.75, 6.66)
2:85924680		W>R	A:41	(4.20, 15.78, 7.48)
2:85924684		R>H	A:42	(10.28, 17.46, 4.65)
2:85924686	COSM1690760	D>N	A:43	(9.26, 20.49, 10.01)
2:85924689		V>I	A:44	(4.90, 19.07, 11.55)
2:85924698		N>H	A:47	(9.31, 18.92, 15.30)
2:85924704	rs143974565	M>L	A:49	(8.87, 10.81, 15.57)
2:85924712	rs532336979	R>S	A:51	(8.21, 17.35, 20.62)
2:85924714		Y>C	A:52	(5.28, 13.00, 21.37)
2:85924722		R>G	A:55	(3.11, 5.47, 23.60)
2:85924729	rs11127	T>I	A:57	(8.83, 2.84, 18.56)
2:85924732		Q>R	A:58	(5.60, 1.56, 23.78)
2:85924735	rs201206149	G>V	A:59	(2.56, 1.07, 20.55)
2:85924740	rs370130578	V>M	A:61	(6.15, -3.30, 19.40)
2:85924741		V>G	A:61	(6.15, -3.30, 19.40)
2:85924747	rs373593126	G>E	A:63	(-0.38, -3.78, 18.39)