General Structure Information
| PDB ID | 1kiv |
| HGNC Gene Label(s) | LPA |
| Structure Name | recombinant kringle iv-10/m66 variant of human apolipoprotein(a) |
| Resolution | 2.1Å |
| Reference | AUTH I.MOCHALKIN,B.CHENG,O.KLEZOVITCH,A.M.SCANU,AUTH 2 A.TULINSKYTITL RECOMBINANT KRINGLE IV-10 MODULES OF HUMANTITL 2 APOLIPOPROTEIN(A): STRUCTURE, LIGAND BINDINGTITL 3 MODES, AND BIOLOGICAL RELEVANCE.REF BIOCHEMISTRY V. 38 1990 1999REFN ISSN 0006-2960PMID 10026282DOI 10.1021/BI9820558 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 78 |
| Number Of SNVs | 14 |
| Number Of Permutations | 2527 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.088 |
| p-value | 0.676 |
COSMIC
| Number Of Residues | 78 |
| Number Of SNVs | 5 |
| Number Of Permutations | 28 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.1 |
| p-value | 0.725 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 14 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | -0.088 |
| p-value | 0.348 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
