General Structure Information
| PDB ID | 1jsg |
| HGNC Gene Label(s) | TCL1A |
| Structure Name | crystal structure of p14tcl1, an oncogene product involved in t-cell prolymphocytic leukemia, reveals a novel b- barrel topology |
| Resolution | 2.5Å |
| Reference | AUTH F.HOH,Y.S.YANG,L.GUIGNARD,A.PADILLA,M.H.STERN,AUTH 2 J.M.LHOSTE,H.VAN TILBEURGHTITL CRYSTAL STRUCTURE OF P14TCL1, AN ONCOGENE PRODUCTTITL 2 INVOLVED IN T-CELL PROLYMPHOCYTIC LEUKEMIA,TITL 3 REVEALS A NOVEL BETA-BARREL TOPOLOGY.REF STRUCTURE V. 6 147 1998REFN ISSN 0969-2126PMID 9519406DOI 10.1016/S0969-2126(98)00017-3 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 111 |
| Number Of SNVs | 35 |
| Number Of Permutations | 3145 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.134 |
| p-value | 0.172 |
COSMIC
| Number Of Residues | 111 |
| Number Of SNVs | 4 |
| Number Of Permutations | 154 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.167 |
| p-value | 0.377 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 35 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.317 |
| p-value | 0.1 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
