General Structure Information
| PDB ID | 1jlm |
| HGNC Gene Label(s) | ITGAM |
| Structure Name | i-domain from integrin cr3, mn2+ bound |
| Resolution | 2.0Å |
| Reference | AUTH J.O.LEE,L.A.BANKSTON,M.A.ARNAOUT,R.C.LIDDINGTONTITL TWO CONFORMATIONS OF THE INTEGRIN A-DOMAINTITL 2 (I-DOMAIN): A PATHWAY FOR ACTIVATION?REF STRUCTURE V. 3 1333 1995REFN ISSN 0969-2126PMID 8747460DOI 10.1016/S0969-2126(01)00271-4 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 187 |
| Number Of SNVs | 51 |
| Number Of Permutations | 4420 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.195 |
| p-value | 0.141 |
COSMIC
| Number Of Residues | 187 |
| Number Of SNVs | 3 |
| Number Of Permutations | 248 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | 0.333 |
| p-value | 0.098 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 51 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.373 |
| p-value | 0.413 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
