General Structure Information
| PDB ID | 1j1d |
| HGNC Gene Label(s) | TNNI3 |
| Structure Name | crystal structure of the 46kda domain of human cardiac troponin in the ca2+ saturated form |
| Resolution | 2.61Å |
| Reference | AUTH S.TAKEDA,A.YAMASHITA,K.MAEDA,Y.MAEDATITL STRUCTURE OF THE CORE DOMAIN OF HUMAN CARDIACTITL 2 TROPONIN IN THE CA2+-SATURATED FORMREF NATURE V. 424 35 2003REFN ISSN 0028-0836PMID 12840750DOI 10.1038/NATURE01780 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 116 |
| Number Of SNVs | 27 |
| Number Of Permutations | 9184 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.262 |
| p-value | 0.178 |
ClinVar
| Number Of Residues | 116 |
| Number Of SNVs | 13 |
| Number Of Permutations | 4467 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | 0.295 |
| p-value | 0.43 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 27 |
| Number Of ClinVar SNVs | 8 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.043 |
| p-value | 0.596 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
