General Structure Information
| PDB ID | 1imh |
| HGNC Gene Label(s) | NFAT5 |
| Structure Name | tonebp/dna complex |
| Resolution | 2.86Å |
| Reference | AUTH J.C.STROUD,C.LOPEZ-RODRIGUEZ,A.RAO,L.CHENTITL STRUCTURE OF A TONEBP-DNA COMPLEX REVEALS DNATITL 2 ENCIRCLED BY A TRANSCRIPTION FACTOR.REF NAT.STRUCT.BIOL. V. 9 90 2002REFN ISSN 1072-8368PMID 11780147DOI 10.1038/NSB749 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 281 |
| Number Of SNVs | 36 |
| Number Of Permutations | 30059 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.057 |
| p-value | 0.361 |
COSMIC
| Number Of Residues | 281 |
| Number Of SNVs | 3 |
| Number Of Permutations | 41 |
| Optimal Distance Threshold | 34.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 36 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | -0.451 |
| p-value | 0.146 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
