General Structure Information
| PDB ID | 1hlg |
| HGNC Gene Label(s) | LIPF |
| Structure Name | crystal structure of human gastric lipase |
| Resolution | 3.0Å |
| Reference | AUTH A.ROUSSEL,S.CANAAN,M.P.EGLOFF,M.RIVIERE,L.DUPUIS,R.VERGER,AUTH 2 C.CAMBILLAUTITL CRYSTAL STRUCTURE OF HUMAN GASTRIC LIPASE AND MODEL OFTITL 2 LYSOSOMAL ACID LIPASE, TWO LIPOLYTIC ENZYMES OF MEDICALTITL 3 INTEREST.REF J.BIOL.CHEM. V. 274 16995 1999REFN ISSN 0021-9258PMID 10358049DOI 10.1074/JBC.274.24.16995 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 368 |
| Number Of SNVs | 89 |
| Number Of Permutations | 9728 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.194 |
| p-value | 0.411 |
COSMIC
| Number Of Residues | 368 |
| Number Of SNVs | 8 |
| Number Of Permutations | 1365 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.25 |
| p-value | 0.926 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 89 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | -0.037 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
