General Structure Information
| PDB ID | 1hig |
| HGNC Gene Label(s) | IFNG |
| Structure Name | three-dimensional structure of recombinant human interferon- gamma. |
| Resolution | 3.5Å |
| Reference | AUTH S.E.EALICK,W.J.COOK,S.VIJAY-KUMAR,M.CARSON,AUTH 2 T.L.NAGABHUSHAN,P.P.TROTTA,C.E.BUGGTITL THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMANTITL 2 INTERFERON-GAMMA.REF SCIENCE V. 252 698 1991REFN ISSN 0036-8075PMID 1902591 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 123 |
| Number Of SNVs | 11 |
| Number Of Permutations | 3850 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.0 |
| p-value | 0.825 |
COSMIC
| Number Of Residues | 123 |
| Number Of SNVs | 5 |
| Number Of Permutations | 525 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.3 |
| p-value | 0.099 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 11 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.409 |
| p-value | 0.038 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
