General Structure Information
| PDB ID | 1hdz |
| HGNC Gene Label(s) | ADH1B |
| Structure Name | three-dimensional structures of three human alcohol dehydrogenase variants: correlations with their functional differences |
| Resolution | 2.5Å |
| Reference | AUTH T.D.HURLEY,W.F.BOSRON,C.L.STONE,L.M.AMZELTITL STRUCTURES OF THREE HUMAN BETA ALCOHOLTITL 2 DEHYDROGENASE VARIANTS. CORRELATIONS WITH THEIRTITL 3 FUNCTIONAL DIFFERENCES.REF J.MOL.BIOL. V. 239 415 1994REFN ISSN 0022-2836PMID 8201622DOI 10.1006/JMBI.1994.1382 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 374 |
| Number Of SNVs | 91 |
| Number Of Permutations | 39466 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.064 |
| p-value | 0.356 |
COSMIC
| Number Of Residues | 374 |
| Number Of SNVs | 13 |
| Number Of Permutations | 10623 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.026 |
| p-value | 0.113 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 91 |
| Number Of COSMIC SNVs | 10 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | -0.094 |
| p-value | 0.117 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
