1H0Z.A | SPINK5

PDB ID	1h0z
HGNC Gene Label(s)	SPINK5
Structure Name	lekti domain six
Resolution	-1.0Å
Reference	AUTH T.LAUBER,A.SCHULZ,K.SCHWEIMER,K.ADERMANN,U.C.MARXTITL HOMOLOGOUS PROTEINS WITH DIFFERENT FOLDS: THETITL 2 THREE-DIMENSIONAL STRUCTURES OF DOMAINS 1 AND 6 OFTITL 3 THE MULTIPLE KAZAL-TYPE INHIBITOR LEKTIREF J.MOL.BIOL. V. 328 205 2003REFN ISSN 0022-2836PMID 12684009DOI 10.1016/S0022-2836(03)00245-6

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
5:147478855		S>P	A:2	(1.24, 7.68, 5.88)
5:147478864	rs529385811	A>T	A:5	(10.57, 6.88, 5.32)
5:147478870	rs375573803	S>T	A:7	(14.27, 1.34, 3.37)
5:147480027	rs2303063	S>N	A:13	(13.99, -7.53, 3.48)
5:147480036		R>Q	A:16	(16.59, -9.03, 0.79)
5:147480053	rs376109480	G>R	A:22	(19.61, -11.61, -8.44)
5:147480056	rs180696183	K>Q	A:23	(15.46, -13.30, -11.86)
5:147480059	rs371578291	L>F	A:24	(12.52, -10.81, -7.06)
5:147480068		T>A	A:27	(2.82, -15.15, -6.22)
5:147480080	rs2303064	D>N	A:31	(-1.72, -5.20, -5.69)
5:147480089	rs371745897	Q>E	A:34	(3.36, 3.57, -7.98)
5:147480093	rs549302486	G>V	A:35	(8.18, 2.52, -7.80)
5:147480100		D>E	A:37	(11.12, 4.20, -11.02)
5:147480123		C>S	A:45	(7.66, -8.68, -6.43)
5:147480130		M>I	A:47	(8.36, -2.37, -6.51)
5:147480935		E>A	A:58	(27.07, -3.64, -6.27)
5:147480944		K>T	A:61	(33.48, -5.17, -7.56)
5:147480950		E>A	A:63	(35.46, -13.08, -3.93)
5:147480955	rs2303067	K>E	A:65	(41.10, -14.92, -11.46)

1H0Z.A | SPINK5.