General Structure Information
| PDB ID | 1gzh |
| HGNC Gene Label(s) | TP53BP1 |
| Structure Name | crystal structure of the brct domains of human 53bp1 bound to the p53 tumor supressor |
| Resolution | 2.6Å |
| Reference | AUTH D.J.DERBYSHIRE,B.P.BASU,L.SERPELL,W.JOO,T.DATE,AUTH 2 K.IWABUCHI,A.J.DOHERTYTITL CRYSTAL STRUCTURE OF HUMAN 53BP1 BRCT DOMAINSTITL 2 BOUND TO P53 TUMOUR SUPPRESSORREF EMBO J. V. 21 3863 2002REFN ISSN 0261-4189PMID 12110597DOI 10.1093/EMBOJ/CDF383 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 213 |
| Number Of SNVs | 39 |
| Number Of Permutations | 6711 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.03 |
| p-value | 0.054 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 39 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.343 |
| p-value | 0.753 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
