General Structure Information
| PDB ID | 1g55 |
| HGNC Gene Label(s) | TRDMT1 |
| Structure Name | structure of human dnmt2, an enigmatic dna methyltransferase homologue |
| Resolution | 1.8Å |
| Reference | AUTH A.DONG,J.A.YODER,X.ZHANG,L.ZHOU,T.H.BESTOR,X.CHENGTITL STRUCTURE OF HUMAN DNMT2, AN ENIGMATIC DNA METHYLTRANSFERASETITL 2 HOMOLOG THAT DISPLAYS DENATURANT-RESISTANT BINDING TO DNA.REF NUCLEIC ACIDS RES. V. 29 439 2001REFN ISSN 0305-1048PMID 11139614DOI 10.1093/NAR/29.2.439 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 311 |
| Number Of SNVs | 84 |
| Number Of Permutations | 22691 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.101 |
| p-value | 0.291 |
COSMIC
| Number Of Residues | 311 |
| Number Of SNVs | 4 |
| Number Of Permutations | 105 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.167 |
| p-value | 0.968 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 84 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 34.0 |
| K Statistic | 0.315 |
| p-value | 0.819 |