General Structure Information
| PDB ID | 1g25 |
| HGNC Gene Label(s) | MNAT1 |
| Structure Name | solution structure of the n-terminal domain of the human tfiih mat1 subunit |
| Resolution | -1.0Å |
| Reference | AUTH V.GERVAIS,D.BUSSO,E.WASIELEWSKI,A.POTERSZMAN,AUTH 2 J.M.EGLY,J.C.THIERRY,B.KIEFFERTITL SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF THETITL 2 HUMAN TFIIH MAT1 SUBUNIT: NEW INSIGHTS INTO THETITL 3 RING FINGER FAMILYREF J.BIOL.CHEM. V. 276 7457 2001REFN ISSN 0021-9258PMID 11056162DOI 10.1074/JBC.M007963200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 65 |
| Number Of SNVs | 8 |
| Number Of Permutations | 552 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.071 |
| p-value | 0.844 |
COSMIC
| Number Of Residues | 65 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 8 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | -0.179 |
| p-value | 0.692 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
