General Structure Information
| PDB ID | 1fzd |
| HGNC Gene Label(s) | FGA |
| Structure Name | structure of recombinant alphaec domain from human fibrinogen-420 |
| Resolution | 2.1Å |
| Reference | AUTH G.SPRAGGON,D.APPLEGATE,S.J.EVERSE,J.Z.ZHANG,L.VEERAPANDIAN,AUTH 2 C.REDMAN,R.F.DOOLITTLE,G.GRIENINGERTITL CRYSTAL STRUCTURE OF A RECOMBINANT ALPHAEC DOMAIN FROM HUMANTITL 2 FIBRINOGEN-420.REF PROC.NATL.ACAD.SCI.USA V. 95 9099 1998REFN ISSN 0027-8424PMID 9689040DOI 10.1073/PNAS.95.16.9099 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 197 |
| Number Of SNVs | 59 |
| Number Of Permutations | 17729 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.14 |
| p-value | 0.877 |
COSMIC
| Number Of Residues | 197 |
| Number Of SNVs | 6 |
| Number Of Permutations | 459 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.333 |
| p-value | 0.692 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 59 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.205 |
| p-value | 0.472 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
