General Structure Information
| PDB ID | 1fnf |
| HGNC Gene Label(s) | FN1 |
| Structure Name | fragment of human fibronectin encompassing type-iii repeats 7 through 10 |
| Resolution | 2.0Å |
| Reference | AUTH D.J.LEAHY,I.AUKHIL,H.P.ERICKSONTITL 2.0 A CRYSTAL STRUCTURE OF A FOUR-DOMAIN SEGMENTTITL 2 OF HUMAN FIBRONECTIN ENCOMPASSING THE RGD LOOP ANDTITL 3 SYNERGY REGION.REF CELL(CAMBRIDGE,MASS.) V. 84 155 1996REFN ISSN 0092-8674PMID 8548820DOI 10.1016/S0092-8674(00)81002-8 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 368 |
| Number Of SNVs | 100 |
| Number Of Permutations | 45543 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.276 |
| p-value | 0.494 |
COSMIC
| Number Of Residues | 368 |
| Number Of SNVs | 5 |
| Number Of Permutations | 3437 |
| Optimal Distance Threshold | 61.0 |
| K Statistic | 0.4 |
| p-value | 0.362 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 100 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 71.0 |
| K Statistic | -0.308 |
| p-value | 0.173 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
