General Structure Information
| PDB ID | 1fg9 |
| HGNC Gene Label(s) | IFNGR1 |
| Structure Name | 3:1 complex of interferon-gamma receptor with interferon- gamma dimer |
| Resolution | 2.9Å |
| Reference | AUTH D.J.THIEL,M.H.LE DU,R.L.WALTER,A.DARCY,C.CHENE,AUTH 2 M.FOUNTOULAKIS,G.GAROTTA,F.K.WINKLER,S.E.EALICKTITL OBSERVATION OF AN UNEXPECTED THIRD RECEPTORTITL 2 MOLECULE IN THE CRYSTAL STRUCTURE OF HUMANTITL 3 INTERFERON-GAMMA RECEPTOR COMPLEX.REF STRUCTURE FOLD.DES. V. 8 927 2000REFN ISSN 0969-2126PMID 10986460DOI 10.1016/S0969-2126(00)00184-2 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 210 |
| Number Of SNVs | 53 |
| Number Of Permutations | 13974 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.123 |
| p-value | 0.41 |
ClinVar
| Number Of Residues | 210 |
| Number Of SNVs | 3 |
| Number Of Permutations | 281 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 1.0 |
| p-value | 0.003 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.946 |
| p-value | 0.005 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
